관련 논문 / 출간물 링크 – 주식회사 케마스

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관련 논문 / 출간물 링크

저희는 의사, 학자, 회사 및 기관과의 파트너십을 발전시키고자 노력하고 있으며,
획기적인 암 치료방법을 지속적으로 연구 및 개발하는 (주)케마스와 뜻이 같은 분들의 협력 제안을 언제든 환영합니다.

Tetraarsenic oxide affects non-coding RNA transcriptome through deregulating polycomb complexes in MCF7 cells. Advances in Biological Regulation. 2021

Tetraarsenic hexoxide enhances generation of mitochondrial ROS to promote pyroptosis by inducing the activation of caspase-3/GSDME in triple-negative breast cancer cells. Cell Death & Disease. 2021

Arsenic hexoxide has differential effects on cell proliferation and genome-wide gene expression in human primary mammary epithelial and MCF7 cells. Scientific Reports. 2021

Anti-Cancer Activity of As4O6 and its Efficacy in a Series of Patient-Derived Xenografts for Human Cervical Cancer. Pharmaceutics. 2020

Anticancer Efficacy of As4O6 in 5637 Human Bladder Cancer Cell Line. 아주대. 2019

Tetraarsenic hexoxide induces G2/M arrest, apoptosis, and autophagy via PI3K/Akt suppression and p38 MAPK activation in SW620 human colon cancer cells. PLoS One. 2017

Inhibition of STAT3/VEGF/CDK2 axis signaling is critically involved in the antiangiogenic and apoptotic effects of arsenic herbal mixture PROS in non-small lung cancer cells. Oncotarget. 2017

Effects of Tetra-arsenic Oxide on Proliferation, Migration and Invasion of Human Breast Cancer MCF-7 Cells. Chinese Journal of Information on TCM. 2017

HER-2/EGFR, the major targets for anti-metastasis effect of tetraarsenic oxide on SKBR3 breast cancer cells. Journal of Chinese Pharmaceutical Sciences. 2017

Tetraarsenic hexoxide demonstrates anticancer activity at least in part through suppression of NF-κB activity in SW620 human colon cancer cells. Oncology Reports. 2015

Tetraarsenic oxide-induced inhibition of malignant glioma cell invasion in vitro via a decrease in matrix metalloproteinase secretion and protein kinase B phosphorylation. Journal of Neurosurgery. 2014

Arsenic hexoxide enhances TNF-α-induced anticancer effects by inhibiting NF-KB activity at a safe dose in MCF-7 human breast cancer cells. Oncology Reports. 2014

Therapeutic efficacy of tetraarsenic hexaoxide (As4O6) in the treatment of acute promyelocytic leukemia in animal model. 과학기술정보통신부 연구자지원사업 보고서. 2013

Tetraarsenic oxide and cisplatin induce apoptotic synergism in cervical cancer. Oncology Reports. 2013

Tetraarsenic hexoxide demonstrates anticancer activities at least in part through suppression of NF-kB-mediated cellular responses in Hep3B human hepatocellular carcinoma cells. Cancer prevention research. 2012

Tetraarsenic Hexoxide Induces Beclin-1-Induced Autophagic Cell Death as well as Caspase-Dependent Apoptosis in U937 Human Leukemic Cells. Evidence-Based Complementary and Alternative Medicine. 2012

Synergistic anti-tumor effects of combination of photodynamic therapy and arsenic compound in cervical cancer cells: in vivo and in vitro studies. PLoS One. 2012

CaSki 세포주에 대한 비소화합물의 세포 성장 억제 및 세포자멸사. 대한산부인과학회지. 2010

자궁경부암 세포주를 이용한 동물모델에서 육산화사비소에 의한 항종양 효과. 인제대학교 의대(산부인과) 박사 논문. 2010

Synergistic interaction between tetra-arsenic oxide and paclitaxel in human cancer cells in vitro. International Journal of Oncology. 2009

Tetra-arsenic oxide (TetraAs) enhances radiation sensitivity of solid tumors by anti-vascular effect. Cancer Letters. 2009

TC-1 세포주를 이용한 동물모델에서 As4O6에 의한 혈관폐쇄 효과. 대한산부회지. 2009

Anti-proliferative Effect of Tetra-arsenic Oxide (TetraAs) in Human Gastric Cancer Cells in Vitro. 약제학회지. 2007

Comparison of diarsenic oxide and tetraarsenic oxide on anticancer effects: relation to the apoptosis molecular pathway. International Journal of Oncology. 2007

Inhibitory effects of tetraarsenic oxide on the growth and metastasis of gastric cancer in SCID mice. Chinese Journal of Experimental Surgery. 2007

Apoptosis-induced Cell Growth Inhibitory Effects of a Novel Compound, As4O6 in a Cervical Cancer Cell Line, SiHa in Vitro. 대한암예방학회지. 2006

흰쥐에서 항암성화합물인 육산화비소의 체내동태. 약제학회지. 2006

Tetraarsenic oxide-mediated apoptosis in a cervical cancer cell line, SiHa. Cancer Research and Treatment. 2005

Diarsenic and tetraarsenic oxide inhibit cell cycle progression and bFGF- and VEGF-induced proliferation of human endothelial cells. Journal of Cellular Biochemistry. 2005

랫드 각막에서 Vascular Endothelial Growth Factor(VEGF)로 유발시킨 신생혈관에 대한 As4O6의 혈관신생 억제효과. 한국임상수의학회지. 2005

방광암 세포주의 세포성장 억제 및 세포고사에 비소화합물이 미치는 영향. 서울대 의대(비뇨기과) 박사 논문. 2004

Reverse effects of tetra-arsenic oxide on the angiogenesis induced by nerve growth factor in the rat cornea. Journal of Veterinary Medical Science. 2004

Comparison of effects of As2O3 and As4O6 on cell growth inhibition and gene expression profiles by cDNA microarray analysis in SiHa cells. Oncology Reports. 2004

교모세포종 세포주에서 육산화비소의 기질금속단백분해효소 분비 억제 및 단백질키나아제 B 인산화 저해를 통한 항침습 효과. 서울대 의대(신경외과) 박사 논문. 2004

Tetraarsenic oxide induces apoptosis in U937 leukemic cells through a reactive oxygen species-dependent pathway. International Journal of Oncology. 2003

Tetraarsenic oxide, a novel orally administrable angiogenesis inhibitor. International Journal of Oncology. 2003

SiHa 세포주에서 비소화합물 (As2O3, As4O6) 투여 후 cDNA microarray를 이용한 유전자 발현의 변화. 대한산부회지. 2002