Publications

We believe in the value of collaboration, particularly if this helps us achieve our goal of continuing to develop breakthrough treatments for cancer. We are keen to develop partnerships with respected doctors and organisations in the industry and we always welcome the opportunity to discuss such collaborations.

  1. Tetra-arsenic hexoxide demonstrates anti-cancer activity at least in part through suppression of NF-KB activity in SW620 human colon cancer cells.
  1. Tetra-arsenic oxide-induced inhibition of malignant glioma cell invasion in vitro via a decrease in matrix metalloproteinase secretion and protein kinase B phosphorylation.
  1. Arsenic hexoxide enhances TNF-α-induced anticancer effects by inhibiting NF-KB activity at a safe dose in MCF-7 human breast cancer cells.
  1. Tetra-arsenic Hexoxide demonstrates anti-cancer activities at least in part through suppression of NF-kB-mediated cellular responses in Hep3B human hepatocellular carcinoma cells
  1. Reverse effects of tetra-arsenic oxide on the angiogenesis induced by nerve growth factor in the rat cornea.
  1. Tetra-arsenic oxide, a novel orally administrable angiogenesis inhibitor
  1. Anti-angiogenic effect of As4O6 on the angiogenesis Induced by vascular endothelial growth Factor (VEGF) in the Rat Cornea.
  1. Vascular shutdown effects by tetra-arsenic oxide in TC-1 cells implanted C57BL/6 mice
  1. Inhibitory effects of tetra-arsenic oxide on the growth and metastasis of gastric cancer in SCID mice
  1. Tetra-arsenic oxide and cisplatin induce apoptotic synergism in cervical cancer.
  1. Synergistic anti-tumor effects of combination of photodynamic therapy and arsenic compound in cervical cancer cells: in vivo and in vitro studies.
  1. Synergistic interaction between Tetra-arsenic oxide and paclitaxel in human cancer cells in vitro.
  1. Tetra-arsenic oxide (TetraAs) enhances radiation sensitivity of solid tumors by anti-vascular effect.
  1. Comparison of diarsenic oxide and Tetra-arsenic oxide on anticancer effects: relation to the apoptosis molecular pathway.
  1. Diarsenic and tetraarsenic oxide inhibit cell cycle progression and bFGF- and VEGF-induced proliferation of human endothelial cells.
  1. Comparison of effects of As2O3 and As4O6 on cell growth inhibition and gene expression profiles by cDNA microarray analysis in SiHa cells
  1. Tetra-arsenic oxide induces apoptosis in U937 leukemic cells through a reactive oxygen species-dependent pathway
  1. The Gene Expression Profile Using cDNA microarray after treatment arsenic compound (As2O3, As4O6) in SiHa Cell.
  1. Apoptosis-induced cell growth inhibitory effects of a novel compound, As4O6 in a cervical cancer cell line, SiHa in vitro
  1. Anti-proliferative effect of tetra-arsenic Oxide (TetraAs) in human gastric cancer cells in vitro
  1. A study on inhibition of cell growth and apoptosis in human cervical cancer cell line (CaSki) by paclitaxel, cisplatin, arsenic trioxide, and Tetra-arsenic oxide
  1. Anti-tumor effect by Tetra-arsenic oxide in animal model implanted with cervical cancer cell line
  1. Tetra-arsenic hexoxide Induces Beclin-1-Induced autophagic cell death as well as caspase-dependent apoptosis in U937 human leukemic cells
  1. Therapeutic efficacy of tetra-arsenic hexoxide (As4O6) in the treatment of acute promyelocytic leukemia in animal model
  1. Pharmacokinetics of Arsenic Hexaoxide, a Anticancer Compound, in Rats
  1. Arsenic trioxide versus tetra-arsenic oxide in biomedical research: misunderstandings and misinterpretations.
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